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Recent evidence on ozone for periodontitis is mixed but potentially useful as an adjunct. A 2025 meta-analysis of 13 randomized trials found that adding ozone to scaling and root planing improved probing depth and gingival index, but not bleeding on probing, plaque index, or clinical attachment level (Liu et al., 2025).

Clear aligners can be as effective as fixed braces for many mild-to-moderate orthodontic problems, but they are not equally predictable for every movement or every severe bite problem. An overview of 18 systematic reviews concluded that clear aligner therapy is effective for selected mild-to-moderate malocclusions, while fixed appliances still have advantages for some complex cases and specific tooth movements (Yassir et al., 2022).

Persistent mouth breathing in children deserves attention because it is associated with differences in craniofacial growth, including a narrower or higher palate, altered jaw position, and certain malocclusions. A 2021 systematic review and meta-analysis pooled 10 studies and found measurable skeletal differences between mouth-breathing and nasal-breathing children (Zhao et al., 2021).

Snoring is common, and sleep-medicine guidance treats it as more than a bedroom nuisance because it can also be a warning sign of obstructive sleep apnea (OSA). American Academy of Sleep Medicine materials cite snoring in up to 30 to 50 percent of adults over age 50 and recommend evaluating symptoms such as loud snoring, witnessed breathing pauses, choking or gasping, and excessive daytime sleepiness when OSA is suspected.